Archive for January, 2010
High irradiances of low-level laser therapy should not be used over melanomas. Researchers studied the pain relieving, anti-inflammatory “cold laser,” finding that it caused increased tumor growth in a mouse model of skin cancer.
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Br J Dermatol. 2009 Oct; 161(4): 918-24
Geng A, Weinstock MA, Hall R, Eilers D, Naylor M, Kalivas J,
BACKGROUND: Topical tretinoin is a medication commonly used for acne that has potential application in the long-term treatment of photodamaged skin. However, there are few published data regarding the tolerability of high-dose tretinoin with long-term use. OBJECTIVES: To assess the long-term tolerability of tretinoin 0.1% cream. METHODS: A randomized, multicentre, double-blind, controlled trial for chemoprevention of keratinocyte carcinomas (i.e. basal cell or squamous cell carcinomas) using topical tretinoin cream to the face and ears was conducted. All participants were veterans and had a history of two or more keratinocyte carcinomas over the previous 5 years. Participants were examined (by a study dermatologist) and interviewed every 6 months (for up to 5.5 years to May 2004). Treatment comprised tretinoin 0.1% cream or vehicle control cream once daily, then twice daily as tolerated. Participants were instructed to step down application frequency to once daily or less if twice daily was not tolerated. The main outcome measures were reported side-effects, frequency of cream application and attendance at study visits. Appropriate data were available for four of the six clinical sites of this trial. RESULTS: Data from 736 randomized participants (mean age 71 years; 97% men) from four clinical sites were analysed. The tretinoin group more commonly reported one or more side-effects at the 6-month follow-up than the control group (61% vs. 42%, P < 0.0001). Side-effects decreased over time in both groups, but to a greater extent in the tretinoin group, and the difference became nonsignificant at 30 months. Burning was the most common side-effect (39% tretinoin vs. 17% control, P < 0.0001). There was no difference in severity of side-effects among those affected. Of the participants who reported burning in either group, most reported mild burning; only 11% of those with burning in the tretinoin group reported it as severe (mild 62% tretinoin vs. 70% placebo; severe 11% vs. 5%; P = 0.4). Itching (24% vs. 16%, P = 0.01) and other local cutaneous reactions (12% vs. 6%, P = 0.01) were also more commonly reported by the tretinoin group at 6 months. There was no difference in numbness (2% vs. 2%, P = 0.9). Participants in the tretinoin group were less likely to apply cream twice daily at 6 months (29% vs. 43%, P = 0.0002). This difference persisted over the entire duration of follow-up. There was little difference between groups in attendance at study visits or completion of telephone interviews (92% vs. 95%, P = 0.06). No unexpected adverse events were reported. CONCLUSIONS: Overall, the tolerability level of topical tretinoin was high in this study population, with almost 40% of the tretinoin group reporting no side-effects, and the majority (67%) tolerating at least once-daily dosing at 6-month follow-up. High-dose topical tretinoin is feasible for long-term use in this population.
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Title: Tapping Into Curry’s Health Benefits
Category: Health News
Created: 11/13/2009 4:10:00 PM
Last Editorial Review: 11/16/2009
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With all the excellent wrinkle skin cream treatments selling today, it is often difficult to even know the real age of an individual. Many wrinkle treatments are often cutting edge products developed by leading scientists who study how your skin grows older. Some of the wrinkle skin cream treatments can be used for a period in your bath room, and there are treatments that are applied by specialists at plush private salons and spas. Lots of treatments have very detailed formulas which are applied in various stages or steps to make them highly effective at reducing the signs of aging.
The old wrinkle formulas that have ingredients that are quite simple. Today there are many options. Some wrinkle treatments are applied topically on the skin while other wrinkle treatments are injected at strategic points in the face. There are even some wrinkle skin cream treatments that may only be used at night.
You can select your wrinkle cream based on several factors. You might want to purchase the most costly wrinkle treatments as you believe that pricey wrinkle creams have more effective ingredients. Better wrinkle skin cream will generally be more expensive because of the costly processing methods of the ingredients and the science behind discovering and formulating them.
If you want to take some of the guess work out of mix you might want to look into some basic helpful tips. Try these more reliable methods to improve and maintain your skin’s health.
Try to shield and protect your skin from the hottest time during the day. Exposure to ultraviolet (UV) light speeds up the natural aging process of your skin. Sun exposure and aging signs go hand and hand. If you protect you skin from the sun it will lessen future wrinkles. Always, use sun lotion (SPF 15+) when out doors even in the winter.
H20 is what your skin needs so give it plenty of water. If you want cut down on wrinkle skin cream usage drink more water. Hydration is critical.
If you do not want crow’s feet wear your sunglasses when going outdoors. Try to keep from excessively pushing or pulling on your face, and from frowning as much as possible. Over the years this will make a significant difference so you might not have to use as much wrinkle skin cream.
Always keep an eye out for new breakthroughs and free trials from cosmetic manufactures. Science is discovering new ways to fight or slow down the aging process all the time and the best weapon against aging is to stay informed.
Look Below for more great articles on wrinkle skin cream
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Tags: I have this extra crease on my eyelids. So it looks like 1 eye is normal and the other has an extra wrinkle which makes it look bigger. Now how do i remove that wrinke?
If you are looking for home remedy to reduce wrinkles, try this.
Smear honey on your face and leave it for as long as possible (but 5-10mins a day will do). then rinse off with tepid water mixed with a teaspoon of cider vinegar – this has a neutral pH and will act as a toner.
And if you have some bucks, Lifecell anti wrinkle cream would be a good choice. You can have more information here.
http://www.lifecellskinreviews.com/
